Elevated levels of biomarkers such as serum amyloid A (SAA), sTREM-1, mannan, anti-mannan antibodies, interleukin-6 (IL-6), interleukin-8 (IL-8), MCP-1, presepsin, and suPAR have been linked to sepsis and are commonly used for early diagnosis and prognostic evaluation [38,39]. The gene discussed is IL6; the disease is Sepsis.