Specifically, carrying the GG or TT genotype for the rs10877012 variant in CYP27B1 confers a 1.7-fold increased susceptibility to hypovitaminosis D (OR = 1.7; CI = 1.1–2.7; TA = 0.57; CVC = 10/10; p = 0.02) compared with carriers of the GT genotype or being a carrier of any other SNVs analyzed (Table 2, Figure 1a). This evidence concerns the gene CYP27B1 and rickets.