PHYHIP and neoplasm: Consistent with the differential gene expression patterns observed in Figure 3b, our analysis of TCGA data in TIMER further validated that MEOX2 (Figure 10a), RBBP8 (Figure 10c), and TCF12 (Figure 10f) were significantly upregulated in tumor tissues, while PHYHIP (Figure 10b), ST18 (Figure 10d), and THRB (Figure 10e) showed marked downregulation.