Silva et al. (2023) [29] associated AA genotypes with methylmercury genotoxicity in the Munduruku-indigenous people, and particularly in the Sawré Aboy villa, a higher frequency of AA and Ag alleles was found together with the highest concentrations of TotalHg and MeHg in hair and blood, associated with a higher risk of neuropathies with somatosensory and cognitive disorders. The gene discussed is RENBP; the disease is cognitive disorder.