TNF and diabetes mellitus: Additionally, positive associations were noted between: EDT and age and diabetes duration (r = 0.416, p < 0.001 and r = 0.290, p = 0.008, respectively), IVRT and HbA1c (r = 0.237, p = 0.036), E/e’ and TNF-alpha (r = 0.260, p = 0.02).