NPPA and cardiac hypertrophy: Inhibiting CD10 can enhance the effects of naturally occurring natriuretic peptides (like atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP)), which help promote natriuresis, induce vasodilation, and decrease cardiac hypertrophy and fibrosis in heart failure patients [134].