IL6 and Behcet disease: Other studies [6] have instead postulated the possible involvement of neuroinflammatory foci in the etiopathogenesis of BD, since subjects with this diagnosis often show high serum levels of proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6).