While TGF-β1 concentrations did not significantly differ between CRRT and non-CRRT groups at either timepoint, there was a significant increase from Day 1 to Day 5 observed exclusively in the non-CRRT group (Δ = +87.1 pg/mL, p = 0.0023), while levels remained unchanged in CRRT patients, thus suggesting impaired or delayed resolution of TGF-β1 signaling in the context of AKI. This evidence concerns the gene TGFB1 and acute kidney injury.