CXCL8 and acute kidney injury: Similarly, patients who developed acute kidney injury (AKI) requiring CRRT had elevated baseline concentrations of CXCL10 (Δ = 3236, 95% CI 1014–5459), IL-10 (Δ = 48.6, 95% CI 34–63), IL-8 (Δ = 39.9, 95% CI 17.7–62.1) and IL-6 (Δ = 1441, 95% CI 125–2697).