While previous studies have demonstrated the ameliorative effects of GP on insulin resistance via modulation of NF-κB and GLUT4 in HepG2 cells [8] and regulation of Akt, IRS-1, and GLUT-1 in in 3T3-L1 adipocytes [9], our study extends these findings in several important ways. The gene discussed is IRS1; the disease is Insulin resistance.