INS and type 2 diabetes mellitus: Finally, Randrianarisoa et al. identified six largely nonoverlapping SNP sets across four AMPK genes (PRKAA1, PRKAA2, PRKAG2, and PRKAG3) associated with adiposity, insulin sensitivity, insulin secretion, and blood glucose, as well as with total, LDL, and HDL cholesterol, in a cohort of 2789 nondiabetic participants from the Tübingen Family study of type 2 diabetes [32].