In 2011, Safranow et al. demonstrated that the prevalence of a variant AMPD1: rs34526199: c.860T allele in Polish CAD patients was significantly lower compared to control subjects; however, in contrast to the AMPD1:rs17602729 polymorphism [1], this genetic variant was associated in these patients with a higher prevalence of diabetes and a higher risk of abdominal obesity [7]. Here, AMPD1 is linked to coronary artery disorder.