While for the rs17602729 polymorphism of the AMPD1 gene the frequency of the variant allele c.34T in the previously analyzed group of CAD patients was similar to its frequency in the current study (16.9% and 15.8%, respectively), it is difficult to explain the differences between these groups for the AMPD1:rs34526199 (c.860A>T) polymorphism where the frequency of the c.860T allele was 1.7% and 4.3%, respectively. The gene discussed is AMPD1; the disease is coronary artery disorder.