IFNG and vitiligo: Under early-stage patient IFN-γ concentrations representative of patient lesional thresholds, low-dose IFN-γ (0.08 ng/mL = 80 pg/mL), approximating early-stage inflammatory conditions, did not affect cell viability significantly, whereas high-dose 10 ng/mL induced substantial melanocyte apoptosis and reduced melanin content (Figure 4A–C) mimics vitiligo lesions.