NPPB and hydrops fetalis: Ianos et al., similarly, highlighted how high NT-proBNP values (above 2379 pg/mL), after adjusting for demographic and clinical covariates, were significantly associated with increased odds of advanced HF and how the measurement of NT-proBNP levels had the highest sensitivity and specificity values (area under the receiver operating curve (AUC) 0.73, 95% C.I. 0.63–0.82), demonstrating not only the diagnostic but also the prognostic role of NT-pro-BNP [37].