In contrast, cardioprotective effects of FF reported for young animals in pathological models of hypertension [13,43,44,53,54,55], myocardial ischemia followed by reperfusion injury [67,68], and diabetes [25,69] have been attributed in part to its ability to enhance mitochondrial function and promote FAO through PPARα activation. Here, PPARA is linked to myocardial ischemia.