For example, Lrrc24 and Ptgfrn are both expressed throughout the lifetime by PCs, but their biochemical function is unknown, while Grfa2 and Itga3 are involved in PC development [28,29] and are downregulated and upregulated, respectively, and Cttnbp2 is a synaptic gene that is downregulated and has been implicated in neurodevelopmental disorders [30,31]. This evidence concerns the gene CTTNBP2 and neurodevelopmental disorder.