In patients with high grade serous ovarian carcinoma (HGSC), epithelial Gal-9 was associated with a lower 5-year overall survival (OS), with a similar negative predictive OS trend observed for plasma Gal-9, thus underscoring its strong prognostic biomarker potential in HGSC [203]. The gene discussed is LGALS9; the disease is ovarian serous carcinoma.