CDH1 and colorectal carcinoma: FadA binds to E-cadherin in order to adhere to epithelial cells; in vitro experiments using CRC cell lines demonstrate the latter event in neoplastic cells induces β-catenin nuclear translocation, thus leading to an increased expression of oncogenes and inflammatory genes belonging to the Wnt pathway, resulting in a powerful proliferative signal in CRC cells [31,46,47,48,49,50,51].