PRMT3 and hepatocellular carcinoma: Finally, one study showed that increasing concentration of SGC707 were effective at decreasing the asymmetric dimethylarginine modification of lactate dehydrogenase A by PRMT3 in hepatocellular carcinoma, dampened any increases in glycolysis in PRMT3 upregulating cells, and mediated and weakened the proliferation capacity of these cells [39].