Angiotensin II subsequently activates the nuclear factor kappa B (NF-κB) pathway, a key regulator of inflammation, which is also stimulated by other cytokines implicated in COVID-19, such as IL-1β, IL-6, TNF-α, IL-10, MCP-1, AT1, and platelet-derived growth factor beta (PDGF-B) [220,221,222]. The gene discussed is IL1B; the disease is COVID-19.