Notably, CST1 isoform is involved in the regulation of key cellular pathways, such as Wnt, GSK3, AKT [46], and IL-6 [47], linking it to inflammatory processes/immunological response [44,48,49,50], cell cycle regulation/cell senescence [51], antimicrobial activity [38,52], cancer progression, and metastatic spread [53,54]. Here, IL6 is linked to cancer.