NFKB1 and cancer: For instance, probiotics have been found to inhibit the nuclear factor-kappa B (NF-κB) [120,122,134,147,148,149], phosphatidylinositol 3-kinase (PI3K)/AKT [122,150], and Wnt/β-catenin pathways [133,151] in malignant cells, thus eliminating cancer progression.