No significant differences between subgroups were observed in sex, body mass index (BMI), waist circumference, waist-to-hip ratio, smoking, dyslipidemia, abdominal obesity, left ventricular hypertrophy (LVH), heart failure with preserved ejection fraction (HFpEF), systolic and diastolic blood pressure, hemodynamic parameters, eGFR, lipid profile, urinary albumin/creatinine ratio (UACR), serum uric acid, creatinine, glucose, calcium and phosphorus levels, Lp(a), soluble suppression of tumorigenicity-2 (sST2), interleukin (IL)-6, fetuin-A, fibroblast growth factor (FGF)-23. The gene discussed is FGF23; the disease is heart failure.