In a univariate logistic regression, low adropin (<2.95 ng/mL), higher levels of hs-CRP (≥5.15 mg/L) and TNF-alpha (≥2.61 pg/mL), as well as a presence of hypertension, T2DM, and HFpEF were found as positive predictors for asymptomatic coronary calcification. This evidence concerns the gene TNF and type 2 diabetes mellitus.