CCL2 and atherosclerosis: Similar results were also found in a recent study conducted by Zhong, et al. [83], who used the same apoE- murine model and found that the combination of FA supplementation (0.006%) and aerobic exercise decreased the aortic root plaque area and plaque burden, as well as the plasma monocyte chemoattractant protein-1 (MCP-1) level, a pro-inflammatory cytokine that increases the progression of atherosclerosis.