However, airway eosinophilia and deposition of eosinophilic peroxidase, although substantially reduced, were not completely abolished and the remaining airway eosinophils collected from the BAL were still able to express IL-5 and IL-3 receptors as well as cytokine receptors, despite treatment with mepolizumab. The gene discussed is IL5; the disease is Increased total eosinophil count.