A majority of DLB patients have two or three concomitant disorders, and neuropathological studies demonstrated the high prevalence of concomitant Alzheimer-related neuropathological changes (ADNC), TAR DNA-binding protein of 43 kDA (TDP-43) [17,18], and other neurodegenerative conditions, including limbic predominant age-related TDP-43 encephalopathy (LATE) [19,20]. Here, TARDBP is linked to Lewy body dementia.