A study computationally investigated a few phytochemical flavonoids to establish their mechanism of action and potential to inhibit AKT1 [31] and showed that tehranolide has a greater capacity to inhibit AKT1 expression, which may be useful in the creation of anticancer drugs because AKT1 inhibition is directly linked to the prevention of tumor growth, progression, and metastasis. This evidence concerns the gene AKT1 and neoplasm.