Of these differentially expressed genes, PDK3 and TNFAIP6 in pGDM and MMP9 and CARD6 in T2D were selected, as they are involved in inflammatory response, glycosylation, and death-like domains based on DAVID and IPA function analyses, which may be involved in the pathological progression to T2D. The gene discussed is PDK3; the disease is type 2 diabetes mellitus.