CCL2 and systemic inflammatory response syndrome: In relation to the delta values of the biomarkers in patients with and without SIRS, important differences were found, with statistically higher medians in patients with SIRS compared to those without SIRS of ∆ HMGB1 [3.58 (0.26–6.5) vs. 0.6 (−1.1–6.5)], ∆ IL-8 [0.3 (−4–0.05) vs. −2 (−8–0.05)], ∆ IL-10 [0.63 (0.21–0.94) vs. 0.08 (−0.19–0.28)], ∆ IL-1β [0.19 (−3.4–0.73 vs. −1.79 (−8–0.1)], and ∆ MCP1 [0.55 (0.22–0.74) vs. 0.42 (0.28–0.95)], * p < 0.05 (Figure 7).