Concerning RAD52, during CML, BCR::ABL-mediated stimulation of single-strand annealing was accompanied by enhanced nuclear colocalization of RAD52 and ERCC excision repair 1 and the endonuclease non-catalytic subunit (ERCC1), which play a key role in DNA repair [69]. Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.