In a large cohort of 14,821 CRC patients, 153 unique RTK fusions were identified, the most common being FGFR1, EGFR, ERBB2, NTRK1, RET, FGFR2, FLT1, FLT3, FLT4, and ALK [16]. The gene discussed is FLT1; the disease is colorectal carcinoma.