Compared to females, IL-6 (Mann–Whitney U = 2653, p = 0.0241) and CRP (Mann–Whitney U = 7350, p = 0.0055) were increased in omicron-variant COVID-19 male patients, while IL-6 also increased in the delta variant (Mann–Whitney U = 3200, p = 0.0254, Figure 4A). Here, IL6 is linked to COVID-19.