Using whole-genome comparative expression profiling, gene expression analysis, and association studies, a significant relationship was identified between single-nucleotide polymorphisms in five genes—ANXA6, COL5A1, ENO1, MYOF, and SCARA5—and bone mineral density and/or osteoporosis in a cohort of 3570 Korean women [33]. Here, COL5A1 is linked to osteoporosis.