The specific mechanisms involve three aspects: first, the expression regulation of RIPK3 (Receptor-Interacting Protein Kinase 3) and its central role in the necroptosis signaling pathway [137]; second, the immune regulatory functions of necroptosis in the tumor microenvironment, including its effects on inflammatory responses and immune cell activation [138]; and, finally, the regulatory effects of necroptosis on the process of tumor metastasis [139]. This evidence concerns the gene RIPK3 and neoplasm.