Cross-trait LDSC analysis unveiled genetic relativity between serum urate concentrations and conditions such as CHD, SAP, UAP, MI, and ischaemic stroke in the European population (range of absolute values of genetic correlation, |0.229| to |0.522|; p = 8.57 × 10−24 to 3.75 × 10−6; Figure 3A; Supplementary Table S4). This evidence concerns the gene UBAP1 and ischemic stroke.