UBAP1 and ischemic stroke: The MR-Egger intercept analysis did not detect any indication of asymmetric horizontal pleiotropy between serum urate concentrations and CHD (egger_intercept p = 0.094), SAP (egger_intercept p = 0.33), UAP (egger_intercept p = 0.28), MI (egger_intercept p = 0.98), and ischaemic stroke (egger_intercept p = 0.276) (Supplementary Table S10).