AKT1 and breast carcinoma: We previously reported that in triple negative MDA-MB-231 breast cancer cells, and the luminal breast cancer subtype cell line MCF7, the CGA and CA combination significantly affected proliferation and caused apoptotic cell death, inhibited cell migration, and shut down the invasive ability of the breast cancer cells, inhibited AKT phosphorylation, and altered the expression levels of EMT transition markers.