SHANK2 and autism: Another study, which provided evidence regarding the association between ncRNAs and autism risk genes, revealed that the administration of exosomal lncRNAs, including the lncRNA IFNG-AS1, in a mouse model of autism restored normal levels of SHANK2, SHANK3, and MECP2 mRNAs, thus ameliorating neuroinflammation and promoting neurogenesis [57].