Although limited by the small sample we were happy to see that CD4+ and CD8+ T lymphocytes number were recovered and, by an yet unknown mechanism, direct infusion of MSC solved partially the lymphopenia demonstrating that despite the big preclinical efforts in characterizing MSC responses, both in-vitro and inside the body, we are still learning on MSC profile and interaction with the body cells, tissues and fluids [95]. This evidence concerns the gene CD4 and lymphopenia.