In the Severe vs. Control group, the genes associated with ER stress, including CLU (p = 0.01), BCL2L1 (p = 0.015), USP14 (p = 0.046), BFAR (p = 0.004), and OPA1 (p = 0.012), demonstrated a significant positive correlation with sepsis score. This evidence concerns the gene BFAR and Sepsis.