This approach extends to other diseases, as seen in studies on nephrotic syndrome using Zhuling Decoction and small cell lung cancer using Cepharanthine, where HMGCR was identified as a hub target involved in the PI3K-Akt, Ras, MAPK, and cholesterol metabolism pathways, respectively [43,51]. Here, HMGCR is linked to small cell lung carcinoma.