Among these, 16 (NFE2L2, SLC7A11, GSK3B, NQO1, AKR1B1, GLS, EGFR, RELA, PRKCB, GCLC, CSNK1A1, MAPK11, MAPK14, CSNK2A1, PRKCA, and JUN) exhibit differential expression in AD, including JUN and NFE2L2. This evidence concerns the gene AKR1B1 and Alzheimer disease.