Xu et al. [153] isolated the following proteins from EVs from HER-2+ BC: cellular response to hydrogen peroxide-related proteins SRC, ARG1, MAPK13, and ErbB2/ErbB3; signaling event-related proteins DOCK7 and SRC; keratinization-related proteins CDSN, KRT78, and KRT23; tyrosine metabolism-related proteins FAH and ADHFE1; and arginine and proline metabolism-related proteins ARG1 and RARS1 (Table 8). The gene discussed is ARG1; the disease is breast cancer.