Reelin production and cleavage, as well as the expression of Aβ1-42, FTH1 and TAU, have been observed in tissues of neuronal derivation when exposed to inflammation, and their dysregulation is more likely to develop neurodegenerative effects (such as in AMD and AD) and warrant further examination [3,58]. This evidence concerns the gene FTH1 and age-related macular degeneration.