The relatively small number of 70 studies with differential expressions detected for genes, shown in Figure 3B, that encode supporting systems, i.e., Na/K-ATPase (9% for five genes), monocarboxylate transporter complex (5% for three genes), lactate dehydrogenases (3% for one gene), taurine transporters (2% for two genes), and 0% for genes encoding functional analogues not listed, support the implication of abnormal K+ flux in cancers with KCN DEGs forcing K+/H+ exchange to initiate pH changes. The gene discussed is SLC6A6; the disease is cancer.