Studies of co-expressed KCNN4, ITGA2, and PLAUR, E8 [172], E41 [162], E49 [166], and E69 [198], included two lung cancers, one melanoma, and one pancreatic cancer, in the categories of His/Chr/Epi, TP53, and RAS (Figure 5A, left Venn diagram). Here, TP53 is linked to familial pancreatic carcinoma.