CD4 and uveitis: Kang et al. [54] analyzed the aqueous humor of patients with uveitis associated with Behcet’s disease (BD) and Vogt–Koyanagi–Harada disease (VKHD), and they noticed that there are distinct landscapes of immune cell infiltration and T-cell clonal expansions between them, with VKHD showing a preference for pro-inflammatory CD4+ Th1 cells and BD for cytotoxic CD8+ T cells, confirming the existence of immunopathogenic discrepancy.