Notably, one study found that individuals with both elevated CRP and sufficient vitamin D had a significantly lower incidence of schizophrenia compared with those with insufficient vitamin D. Participants with an elevated CRP and reduced 25(OH)D levels had the highest prevalence of schizophrenia, while the lowest prevalence was seen in participants with reduced CRP and an elevated 25(OH)D [34]. The gene discussed is CRP; the disease is schizophrenia.