Because we observed no effect on cell viability in vitro or tumor growth in vivo with EphA2 KO in our KPL lung model, perhaps EphA2 is playing a dual tumor promoter and suppressor role in this cell line, whereas, in KPCY pancreatic tumors, EphA2 is more of a tumor promoter than suppressor. Here, EPHA2 is linked to neoplasm.