PRF1 and lung adenocarcinoma: Lastly, although the authors observed inverse correlations between EPHA2 and CTL gene signatures in human pancreatic cancer, we did not discover any consistent trends between EPHA2 and CD3E, CD8B, GZMA, GZMB, PRF1, or IFNG expression from the TCGA lung adenocarcinoma dataset (Figure S5).