Conversely, a homogeneous disorganized pattern was significantly associated with increased risk of NRAS mutated melanoma (OR = 6.96, 95% CI: 1.49–32.53; p = 0.014), whereas a multicomponent pattern was significantly associated with a reduced risk of NRAS mutated melanoma (OR = 0.16, 95% CI: 0.03–0.83; p = 0.029). Here, NRAS is linked to melanoma.