HDAC1 and hepatocellular carcinoma: For example, peptides obtained from Alcalase-hydrolyzed maize albumin were shown to induce apoptosis in human hepatocellular carcinoma HepG2 cell lines, whereas quinoa-derived peptides suppressed cancer cell proliferation by inhibiting an enzyme regulating gene expression, namely histone deacetylase 1 (HDAC1), downregulating many inflammatory genes expression, and triggering apoptosis in a human colorectal adenocarcinoma cell line called Caco-2 [25,26].