ERN1 and neoplasm: At the same time, in the RLS40 model, DNase treatment resulted in a decrease in the mRNA levels of pro-tumor phenotype markers (Ccl17, Il10) and an increase in the mRNA levels of anti-tumor phenotype markers (Icam1, Tnfa, Vegfr1), as well as cell mobilization genes (Ern1, Stat3).