TP53 and breast cancer: We also predicted and examined the key genes (e.g., SRRM2, HUWE1, KMT2D) and biological pathways regulated by these DE miRNAs, including the MAPK signaling pathway, cell cycle, Wnt signaling pathway, PI3K-Akt signaling pathway, breast cancer pathway, apoptosis, TGF-beta signaling, p53 signaling, Hedgehog signaling, Notch signaling, and estrogen signaling pathways.