Additionally, collagen proteins (COL1A1, COL1A2, COL3A1, COL11A1) were linked to tumor progression and metastasis, while chaperonin-containing TCP1 (CCT) complex proteins and microtubule-associated proteins (TUBA1C, TUBB) were implicated in cytoskeletal organization and chemotherapy resistance. The gene discussed is TUBB; the disease is neoplasm.